In conclusion, although EMR exposure decreased the prolactin, estrogen, and progesterone levels in the plasma of maternal rats and their offspring, EMR-induced oxidative stress in the uteri of maternal rats increased during the development of offspring. Mobile phone- and Wi-Fi-induced EMR may be one cause of increased oxidative uterine injury in growing rats and decreased hormone levels in maternal rats. TRPV1 cation channels are the possible molecular pathways responsible for changes in the hormone, oxidative stress, and body temperature levels in the uterus of maternal rats following a year-long exposure to electromagnetic radiation exposure from mobile phones and Wi-Fi devices. It is likely that TRPV1-mediated Ca2+ entry in the uterus of pregnant rats involves accumulation of oxidative stress and opening of mitochondrial membrane pores that consequently leads to mitochondrial dysfunction, substantial swelling of the mitochondria with rupture of the outer membrane and release of oxidants such as superoxide (O2 -) and hydrogen peroxide (H2O2). The superoxide radical is converted to H2O2 by superoxide dismutase (SOD) enzyme. Glutathione peroxidase (GSH-Px) is an important antioxidant enzyme for removing lipid hydroperoxides and hydrogen peroxide and it catalyzes the reduction of H2O2 to water.

Remarkably, cell phones had been allowed onto the US consumer market a decade earlier without any government safety testing. Now, some customers and industry workers were being diagnosed with cancer. In January 1993, David Reynard sued the NEC America Company, claiming that his wife’s NEC phone caused her lethal brain tumor. After Reynard appeared on national TV, the story went viral. A congressional subcommittee announced an investigation; investors began dumping their cell-phone stocks; and Wheeler and the CTIA swung into action.2
A 2012 study by NCI researchers (25) compared observed glioma incidence rates in U.S. SEER data with rates simulated from the small risks reported in the Interphone study (6) and the greatly increased risk of brain cancer among cell phone users reported in the Swedish pooled analysis (19). The authors concluded that overall, the incidence rates of glioma in the United States did not increase over the study period. They noted that the US rates could be consistent with the small increased risk seen among the subset of heaviest users in the Interphone study. The observed incidence trends were inconsistent with the high risks reported in the Swedish pooled study. These findings suggest that the increased risks observed in the Swedish study are not reflected in U.S. incidence trends.
This study used Drosophila as model organisms to assess the effects of various EMF sources (short time daily for 3-7 days) on apoptotic cell death of follicles during oogenesis and reproductive capacity (fecundity) decline. Sources included: 900/1800 MHz mobile phone, 1880-1900 MHz wireless base, wireless handset, mobile phone-handset combination, 2.44 GHz wireless network (Wi-Fi), 2.44 GHz bluetooth, 92.8 MHz FM generator, 27.15 MHz baby monitor, 900 MHz CW RF generator and microwave oven’s 2.44 GHz RF and magnetic field components. All EMF sources used created statistically significant effects regarding fecundity and cell death-apoptosis induction, even at very low intensity levels well below ICNIRP’s guidelines, suggesting that Drosophila oogenesis system is suitable to be used as a biomarker for exploring potential EMF bioactivity.
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The highest typical daily exposure, according to a study of 2009, came from cellphone base stations, cellphones and DECT cordless phones, with the highest exposure locations in trains, airports and buses.[17] The typical background power of electromagnetic fields in the home can vary from zero to 5 milliwatts per meter squared.[citation needed] Long-term effects of these electromagnetic fields on human and animal health are still unknown.
The authors of these studies noted that the results were preliminary and that possible health outcomes from changes in glucose metabolism in humans were unknown. Such inconsistent findings are not uncommon in experimental studies of the biological effects of radiofrequency electromagnetic radiation in people (4). Some factors that can contribute to inconsistencies across such studies include assumptions used to estimate doses, failure to consider temperature effects, and lack of blinding of investigators to exposure status.
Users of wireless devices are typically exposed for much longer periods than for mobile phones and the strength of wireless devices is not significantly less. Whereas a Universal Mobile Telecommunications System (UMTS) mobile phone can range from 21 dBm (125 mW) for Power Class 4 to 33 dBm (2W) for Power class 1, a wireless router can range from a typical 15 dBm (30 mW) strength to 27 dBm (500 mW) on the high end.[6]

We investigated the effect of olive leaves extract administration on glucose metabolism and oxidative response in liver and kidneys of rats exposed to 2.45 GHz radiofrequency radiation (1h/day for 21 days). This exposure was shown to induce a diabetes-like status and also decreased the activities of glutathione peroxidase, catalase, superoxide dismutase, and groups thiol amount in liver and kidneys. Olive leaves extract administration (100 mg/kg, ip) in RF-exposed rats prevented glucose metabolism disruption and restored the activities of GPx, CAT and SOD and thiol group amount in liver and kidneys and was able to bring down the elevated levels of MDA in liver but not in kidneys. Our investigations suggested that RF exposure induced a diabetes-like status through alteration of oxidative response, while olive leaves extract was able to correct glucose metabolism disorder by minimizing oxidative stress induced by RF in rat tissues.
Repeated Wi-Fi studies show that Wi-Fi causes oxidative stress, sperm/testicular damage, neuropsychiatric effects including EEG changes, apoptosis, cellular DNA damage, endocrine changes, and calcium overload. Each of these effects are also caused by exposures to other microwave frequency EMFs, with each such effect being documented in from 10 to 16 reviews. Therefore, each of these seven EMF effects are established effects of Wi-Fi and of other microwave frequency EMFs. Each of these seven is also produced by downstream effects of the main action of such EMFs, voltage-gated calcium channel (VGCC) activation. While VGCC activation via EMF interaction with the VGCC voltage sensor seems to be the predominant mechanism of action of EMFs, other mechanisms appear to have minor roles. Minor roles include activation of other voltage-gated ion channels, calcium cyclotron resonance and the geomagnetic magnetoreception mechanism. 
The aim of this study was to investigate long-term effects of 2.4 GHz radiofrequency radiation (24 h/day for 1 year) emitted from a Wireless Fidelity (Wi-Fi) system on the testes of male rats. Results showed that sperm head defects increased in the exposure group (p < 0.05) while weight of the epididymis and seminal vesicles, seminiferous tubules diameter and tunica albuginea thickness were decreased in the exposure group (p < 0.01, p < 0.001, p < 0.0001). However, other alterations of other parameters were not found significant (p > 0.05). We suggest Wi-Fi users to avoid long-term exposure of RF emissions from Wi-Fi equipment.
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“There are 25,000 brain tumor cases in India’s Andhra Pradesh and Telangana states, and most of them are attributed to excessive use of cell phones, as per a recent medical survey”. Girish Kumar said that World Health Organization warned of increasing risk of cell phone brain tumor and cancer cases caused by the use of cell phones and location of cell towers in residential areas.