We aimed to investigate the protective effects of melatonin and 2.45 GHz electromagnetic radiation (60 min/day for 30 days) on brain and dorsal root ganglion (DRG) neuron antioxidant redox system, Ca(2+) influx, cell viability and electroencephalography (EEG) records in the rat. Lipid peroxidation (LP), cell viability and cytosolic Ca(2+) values in DRG neurons were higher in EMR-exposed groups than in controls, although their concentrations were increased by melatonin, 2-aminoethyldiphenyl borinate (2-APB), diltiazem and verapamil supplementation. Lower numbers of EEG spikes were recorded in EMR+melatonin groups than in EMR only, while brain cortex vitamin E concentrations were higher in the melatonin-supplemented group. In conclusion, Melatonin supplementation in DRG neurons and brain seems to have protective effects on the 2.45 GHz-induced increase Ca(2+) influx, EEG records and cell viability of the hormone through TRPM2 and voltage gated Ca(2+) channels.
According to the results of the current research, long-term exposure to EMR emitted from wireless devices had adverse effects on the antioxidant potential of blood. Therefore, to protect individuals from harmful effects of Wi-Fi signals, it is advised to limit the use of such devices for household and occupational activities, if possible. This study may stimulate future helpful research in the development of new protective or therapeutic approaches. In addition, it is recommended that the target tissues of EMR emitted from wireless devices and the level of other mediators be investigated to understand the exact molecular mechanism and site of action upon continuous exposure to such radiations.

In today's world, 2.45-GHz radio-frequency radiation (RFR) from industrial, scientific, medical, military and domestic applications is the main part of indoor-outdoor electromagnetic field exposure. Long-term effects of 2.45-GHz Wi-Fi radiation on male reproductive system was not known completely. Therefore, this study aimed to investigate the major cause of male infertility during short- and long-term exposure of Wi-Fi radiation.


In 2015, scientists from around the world united for the International EMF Scientist Appeal based on the results of over 2,000 research papers. The appeal is the collective voice of 190 scientists from 39 different countries. They are calling for tighter regulations and more security measures when dealing with electromagnetic field exposures generally, and WiFi in particular.
Cancer is the obvious start. An early concern with mobile technology was clusters of the disease around those living near phone masts. One study in Israel found a 4.5-fold increase in cancers of all kinds in the immediate vicinity of a mast (Int. J. Cancer Prev., 2004). In 2009, a Korean team of researchers carried out a pool analysis of the results of 23 studies, which involved almost 38,000 subjects.  
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