This study was performed to understand the effect of short (15 days) and long-term (30 and 60 days) low-level 2.45 GHz MW radiation exposure on hippocampus with special reference to spatial learning and memory and its underlying mechanism in Swiss strain male mice, Mus musculus. We observed that, short-term as well as long-term 2.45 GHz MW radiation exposure increases the oxidative/nitrosative stress leading to enhanced apoptosis in hippocampal subfield neuronal and nonneuronal cells. Present findings also suggest that learning and spatial memory deficit which increases with the increased duration of MW exposure (15 < 30 < 60 days) is correlated with a decrease in hippocampal subfield neuronal arborization and dendritic spines. These findings led us to conclude that exposure to CW MW radiation leads to oxidative/nitrosative stress induced p53-dependent/independent activation of hippocampal neuronal and nonneuronal apoptosis associated with spatial memory loss.
Nevertheless, a group of scientists got together in the mid-2000s, calling themselves the BioInitiative Working Group. This group, which largely consisted of wireless radiation researchers, has written a harsh reply as feedback to the reports claiming that posed no health risks.  The reply lists a wide range of health effects scientists at the European Commission have unfortunately either ignored or dismissed.