Due to the relatively recent adoption of cell phones, the long-term safety of the technology cannot be determined conclusively and caution is warranted. Research on glioma brain tumors shows the average latency period is 20-30 years.  Although cell phones were introduced in 1983, it was not until 2003 that over 50% of the US population had a wireless subscription, so the 20 year mark for mass cell phone use has not yet been reached.   The May 17, 2010 INTERPHONE study, the largest study ever to examine possible links between cell phones and brain tumors, concluded that overall there was "no increase in risk" for glioma or meningioma brain tumors,  but the average user in the study had less than eight years of cell phone exposure.  In his review of the INTERPHONE study results, Dr. Rodolfo Saracci stated that "none of today’s established carcinogens, including tobacco, could have been firmly identified as increasing risk in the first 10 years or so since first exposure." 
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Based on the DNA damage results determined by the single cell gel electrophoresis (Comet) method, it was found that the% tail DNA values of the brain, kidney, liver, and skin tissues of the rats in the experimental group increased more than those in the control group. The increase of the DNA damage in all tissues was not significant (p>0.05). However the increase of the DNA damage in rat testes tissue was significant (p<0.01).
The most compelling evidence though comes from a Swedish team of cancer experts whose research stretches back 15 years. The results clearly demonstrate “a consistent association between long-term use of cell phone and cordless phones and glioma and acoustic neuroma”. Overall, they found that using a cell phone for more than a decade significantly increases the risk of a malignant tumour by almost two times with an analogue cell phone and by nearly four times with a digital phone. Interestingly, the risks were even higher for people who had started using mobiles as teenagers.